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| CAKEBUSH TINCTURE (tinctura Piper marginatum) from AMAZON HERBS® |
OverviewPiper marginatum is a medicinal plant from the Amazon rainforest; used to relieve pain, swelling and fever; it is haemostatic (substance used to stem internal bleeding), repellent, antibiotic and antifungal. It has a strong licorice (anise) smell and can be used to treat skin infections. It has carminative and antispasmodic action. Oils from this plant have strong cercaricidal (an agent lethal to cercaria) activity. Traditional use in the Amazon rainforest include against liver and vesicle disease. Constituents It has 39 constituents of the essential oils. Phenylpropanoids, and a new phenyloctanoid were isolated from Piper marginatum. The compounds: 3,4-methylenedioxy-1-(2E-octenyl)-benzene 2,6-dimethoxy-3,4-methylenedioxy- 1-(2-propenyl)-benzene, 1 -(1E-propenyl)-2,4,6-trimethoxybenzene: apiole; isoasarone. Croweacin (2-methoxy-3,4-methylenedioxyallylbenzene). 1-(1Z-propenyl)-2,4,6-trimethoxybenzene, 3-farnesyl-4-hydroxybenzoic acid, caryo-phylene oxide. Pharmacology In Brazilian folk medicine, this plant is reputed for its analgesic/anti-inflammatory properties. The roots are used as diuretic; extract of the leaves prepared in hot water is used to treat toothache, rheumatism, tumor and bleeding skin wounds. From the roots of Piper marginatum, cioweacin, apiole, isoasarone, pipern~argine, marginatine and N-isobutyl-2-trans-4-trans-octadienaniide were isolated (the only amide detected in this plant). Since 2,4,5-trioxiphenylpropanoids as y-asarone, a-asarone and asaricin has been reported to have antimicrobial activities against Escherichia coli and Bacillus subtilis 11, 2-methoxy- 4,5-metylenedioxypropiophenonem, may be an explanation for some activities showed by Piper marginatum. Dosage Tincture: 1 - 3 ml (1 – 3 full droppers), daily. Precaution None. Reference Croweacin from Piper marginatum*¹ Bárbara Viviana de Oliveira Santos± Emidio V. L. Da-Cunha±, Maria Célia de Oliveira Chaves± and Alexander I. Gray W. Baker, A. R. Penfold and J. L, Simonsen, J. Chem. Soc., 439 (1939) A. J. Birch and M. Slaytor, Chem, Ind. (London), 1524 (1956) A. T. Shulgin, Nature, 197, 379 (1963) A. T. Shulgin, Can. J. Chem., 43, 3437 (1965) F. Mauthner, J. Prakt. Chem., 102, 41 (1921); T. Takahashi, J. Chem. Soc. Japan, 50, 356 (1929) W. N. White and C. D. Slater, J. Org. Chem., 26, 3631 (1961) The above presentation is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. For many of the conditions discussed, treatment with prescription or over - the - counter medication is also available. Consult your doctor, practitioner, and / or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications. |
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