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SPIGELIA TINCTURE (tinctura Spigelia anthelmia) from AMAZON HERBS® |
OverviewSpigelia (Demerara pinkroot), a powerful anthelmintic, but it exerts also a powerful action on the nervous system. It is known primarily in homeopathy as a medicine for left-sided face pain. It has marked elective affinity for the eye, heart, and nervous system. Neuralgia of the fifth nerve is very prominent in its effects. Is adapted to anemic, debilitated, rheumatic, and scrofulous subjects. Stabbing pains. Used as a vermifuge (treatment for worms); it also has an important role in cardiac treatment It is a major drug for pericarditis*; Constituents General: alkaloids, tannins, saponins, steroids, phlobatannin, flavonoids, cardic-glucoside. Spiganthine, ryanodine, 20-Deoxyspiganthine; 8a-Hydroxyspiganthine; 20-Norspiganthine-5-carboxylic acid; Ryanodine; 10-epi-Ryanodine; 8,9-Dehydro-10-epi-ryanodine; 20-Hydroxyryanodine Detailed phytochemical analysis of extracts of the aerial parts of Spigelia anthelmia L. yielded 20 structurally related new compounds, besides spiganthine and ryanodine. Pharmacology Spiganthine was isolated as the main cardioactive principle from medicinally used extracts of Spigelia anthelmia. The biological effect of spiganthine is characterized by a delay in contraction development of the heart muscle. Alkaloids from Demerara pinkroot make it effective against heart disease. Other heart problems, such as mururs, rheumatic heart disease, angina, and valve disorders have been treated. It can help relieve chest pain, especially that which extends into the chest, arms, and throat, as well. Applications (Rheumatic) pericarditis, endocarditis, rheumatic ophthalmia and facial neuralgia. In rheumatic fever, with little inflammatory swelling of the joints. In palpitations arising from mitral and aortic disease. Used as a vermifuge. Dosage Tincture: check with your homeopath! Infusion: *The pericardium is a thin layer of tissue that covers the outer surfaces of the heart. It helps to hold the heart in place; prevents excessive movement of the heart in the chest, protects the heart from infections and tumors that develop in it and may spread from adjacent tissues. It may help keeping the heart from enlarging. Inflammation of the pericardium is called pericarditis. Precaution As a homeopathic remedy, only to be used under supervision of a homeopath. For more information on Spigelia, go to the "MAROWINA FACTS® DATABASE". Reference Spiganthine, the cardioactive principle of Spigelia anthelmia. Achenbach H, Hubner H, Vierling W, Brandt W, Reiter M. Neuromuscular effects and acute toxicity of an ethyl acetate extract of Spigelis anthelmia Linn. Camurca-Vasconcelos, A.L.F., Nascimento, N.R.F., Sousa, C.M., Melo, L.M., Morais, S.M., Bevilaqua, C.M.L., Rocha, M.F.G. Journal of Ethnopharmacology Minor constituents of Spigelia anthelmia and their cardiac activities. Hubner H, Vierling W, Brandt W, Reiter M, Achenbach H. Department of Pharmaceutical Chemistry, University of Erlangen, Germany. Huebner@pharmazie.uni-erlangen.de Spiganthine, the cardioactive principle of Spigelia anthelmia. Achenbach H, Hubner H, Vierling W, Brandt W, Reiter M. Institut fur Pharmazie und Lebensmittelchemie der Universitat Erlangen, Germany. Anthelmintic efficacy of extracts of Spigelia anthelmia Linn on experimental Nippostrongylus braziliensis in rats. Olorunfemi Cornelius Jegede¹,*, Joseph Ologunja Ajanusi², Ambrose. O. Adaudi¹, Rowland I. S. Agbede² The above presentation is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. For many of the conditions discussed, treatment with prescription or over - the - counter medication is also available. Consult your doctor, practitioner, and / or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications. |
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