Tropilab Inc.

APPLICATIONS AND DOSAGE.

ZINGIBER OFFICINALE - GINGER
(100 % Zingiber officinale root powder)

Overview:

Ginger is used as an aromatic carminative and pungent appetite stimulant; it is also a remedy for digestion.
Ginger is effective against nausea and vomiting associated with motion sickness, pregnancy, and postoperative recovery; it also may be effective and safe for chemotherapy-induced nausea and vomiting.
It may effectively be used for patients who continue to experience delayed nausea and vomiting despite treatment with other less effective anti-nausea drugs.

Phytochemicals:
Volatile oils (bisabolene, cineol, phellandrene, citral, borneol, citronellol, geranial, linalool, limonene, zingiberol, zingiberene, camphene), Oleoresin (gingerol, shogaol), Phenol (gingeol, zingerone), Proteolytic enzyme (zingibain), Vitamin B6, Vitamin C, Calcium, Magnesium, Phosphorus, Potassium, Linoleic acid. The pungency of ginger is due to GINGEROL which is the alcohol group of the oleoresin.
Ginger owes its aroma to about 1 to 3% of volatile oils, these are bisabolene, zingiberene and zingiberol.

Pharmacology:
Anti-tumor: it is one of the herbs possessing the highest anti-tumor activities.
Gingerols are the main active components in Ginger and responsible for its distinctive flavor, it may also inhibit the growth of human colorectal cancer cells.
Results suggest that Ginger compounds may be effective chemopreventive and/or chemotherapeutic agents for colorectal carcinomas
Anti-inflammatory: gingerol is capable of suppressing the inflammatory effect of severe arthritis were treated with Ginger oil
Ginger may help, suggests a study published in a recent issue of Osteoarthritis Cartilage
Antioxidant: A number of animal studies have shown that Ginger lowers cholesterol levels.
Experimental animal data suggest a strong positive effect of the Ginger on plasma lipid composition that may be important for the prevention of atherosclerotic events
Nausea: prevent postoperative nausea and vomiting in women
Motion sickness: for preventing seasickness and motion sickness

Applications:
Against cholesterol, liver - and gallbladder problems: 30 drops (1 ml), 3 times daily
Against cancerous tumors: 2 -4 ml daily.

Dosage:
Tincture: 2 - 3 ml. daily (1 – 3 full droppers)
Infusion: 1 – 2 cups daily.

Precautions /drug interactions:
Ginger can enhance the anticoagulant effect of Warfarin, leading to an increased risk of bleeding.
H2-blockers / Proton pump inhibitors: Ginger may antagonize activity by increasing stomach acid production.
Antihypertensives: Ginger may cause additive hypotensive effects.
Hypoglycemics / Insulin: Ginger may cause additive reductions in blood glucose

References:
• Akoachere JF, Ndip RN, Chenwi EB et al. Antibacterial effect of Zingiber officinale and Garcinia kola on respiratory tract pathogens. East Afr Med J. 2002 Nov;79(11):588-92.
• Bode A Ginger is an effective inhibitor of HCT116 human colorectal carcinoma in vivo. paper presented at the Frontiers in CancerPrevention Research Conference, Phoenix, AZ, Ocbober 26-3-, 2003.
• Ensminger AH, Ensminger, ME, Kondale JE, Robson JRK. Foods & Nutriton Encyclopedia. Pegus Press, Clovis, California.
• Ensminger AH, Esminger M. K. J. e. al. Food for Health: A Nutrition Encyclopedia. Clovis, California: Pegus Press; 1986.
• Ficker CE, Arnason JT, Vindas PS et al. Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Mycoses. 2003 Feb;46(1-2):29-37.
• Fischer-Rasmussen W, Kjaer SK, Dahl C, et al Ginger treatment of hypereesis gravidarum. Eur J Obstet Gynecol Reprod Biol 38(1990):19-24.
• Fortin, Francois, Editorial Director. The Visual Foods Encyclopedia. Macmillan, New York.
• Grieve M. A Modern Herbal. Dover Publications, New York.
• Ippoushi K, Azuma K, Ito H, Horie H, Higashio H. [6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactions. Life Sci. 2003 Nov 14;73(26):3427-37.
• Jagetia GC, Baliga MS, Venkatesh P, Ulloor JN. Influence of ginger rhizome (Zingiber officinale Rosc) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat Res. 2003 Nov;160(5):584-92.
• Kiuchi F, et al. Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull 40 (1992):387-91.
• Nature Immunology Online. Nature Immunology Online. 2001;10.1038/ni732. • Srivastava KC, Mustafa T. Ginger(Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypothesis 39(1992):342-8.
• Srivastava KC, Mustafa T. Giner (Zingiber officinale) and rheumatic disorders. Med Hypothesis 29 (1989):25-28.
• Wigler I, Grotto I, Caspi D, Yaron M. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage. 2003 Nov;11(11):783-9.
• Wood, Rebecca. The Whole Foods Encyclopedia. New York, NY: Prentice-Hall Press; 1988.


The above presentation is for informational and educational purposes only.
It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage.
For many of the conditions discussed, treatment with prescription or over - the - counter medication is also available.
Consult your doctor, practitioner, and / or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications

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