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GRAINS OF PARADISE TINCTURE (tinctura Aframomum melegueta) from AMAZON HERBS® |
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Overview)
Aframomum Melegueta aka Grains of Paradise is an herbaceous perennial plant in the Ginger family
with many medicinal benefits. The seeds and rhizomes are used in West African and Surinamese Traditional Medicine.The rhizomes show antimicrobial and antifungal activity and the herbal dietary supplement (tincture) is effective against schistosomiasis (bilharzia). The leaves of this plant are used for the therapy of measles. It is used as a purgative, galactogogue (increases production of breast milk), anthelmintic- and hemostatic agent (purifies the blood). Also used against intestinal infections and infestations. The seeds have anti-inflammatory activity with a favorable gastric tolerability profile. It works in a similar way as the well-known anti-inflammatory drugs. In Africa it is also used for the therapy of leprosy, and to expel tapeworms. Constituents Essential oils (Gingerol, Shogaol, Paradol, Gingeredione, Zingerone), alkaloids, cardiac glycosides, tannins, flavonoids, sterols, triterpenes, oils, glycosides, tannins, flavonoids, sterols, resins. Pharmacology )
The seeds have general anti-microbial properties similar to many spices; they have molluscicidal
and repellant properties as well.The antimicrobial activity of Aframomum melegueta seed extract compared favorably with that of the drug Streptomycin (Streptomycin sulfate) on tested organisms. Streptomycin is an antibiotic (antimycobacterial) drug with serious side effects though. Aframomum melegueta methanolic and chloroform extracts hold cytotoxic potential against PANC-1 pancreatic cancer cells. A methanol extract and fractions (pet ether and methanol) of Aframomum melegueta K. Schum (Zingiberaceae) seeds were evaluated for anti-inflammatory activity. An acute toxicity test in mice was used to establish an i.p. LD50 of 2154 mg/kg for the methanol extract. Phytochemical analysis of the methanol extract revealed the presence of alkaloids, glycosides, tannins, flavonoids, sterols, triterpenes, and oils, while the methanol fraction contained alkaloids, glycosides, tannins, flavonoids, sterols, and resins. The results indicate that the seeds possess potent anti-inflammatory activity with a favorable gastric tolerability profile. The oleoresin obtained from Aframomum contains volatile oil, is rich in paradols, gingerols and shogaols (Ghana Herbal Pharmacopoiea). Grains of Paradise is also included in most effective herbal mixes to shrink fibroids, non-cancerous (benign) tumors, growing from the muscle layers of the uterus. Research from the National Institute of Allergy and Infectious Diseases Research has shown that Aframomum has significant antimicrobial activity. The plant works against the microbe responsible for the hard-to-manage infection, Methicillin Resistant Staphylococcus Aureus (MRSA). It has reached epidemic levels in some hospitals and other confined places. It is also impervious to every penicillin-like antibiotic now available. The Japanese Society of Nutrition has found that Aframomum melegueta (Alligator pepper) has the ability to lower body fat percentage, and decreased waist-hip ratio without any harmful side effects. Applications In Ghana, seeds are chewed to halt dysentery, as a sedative against toothache, anti-rheumatism and migraine. In African Traditional Medicine, Atare (Alligator pepper) is safely used for males having problems with erectile dysfunction, premature ejaculation and as an aphrodisiac. Used successfully against MRSA, a bacterium resistant to many antibiotics. Most MRSA infections are skin infections. In medical facilities, MRSA causes life-threatening bloodstream infections, pneumonia and surgical site infections. Dosage Herbal tincture: 1 - 2 ml. (1 - 2 full droppers daily). Infusion (herbal tea): 1 - 2 cups daily. Precaution Large quantities of alligator pepper pose a health risk to women in their first trimester of pregnancy. There is risk for adverse drug-drug interactions. Reference In situ Morphometric Characterization of Aframomum melegueta. K. Schum Accessions in Ghana; J. Amponsah, N. Adamatey, W. Elegba, K. E. Danso. Phytochemical composition of Aframomum melegueta and Piper guineense seeds. Ekpo IA, Osuagwu AN, Agbor RB, Okpako EC, Ekanem BE. The above presentation is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. For many of the conditions discussed, treatment with prescribed (RX) or over-the-counter medication (OTC) is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications. |
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